Thonburi Trang

 Most hepatocellular carcinoma (HCC) grows on chronic liver disease. Early-stage tumors are treatable—if you look for them. That’s why people at risk need a tight, repeatable plan.

High-risk groups

• Chronic hepatitis B or C

• Cirrhosis of any cause

• Heavy alcohol use

• Fatty liver / diabetes / obesity (NAFLD/NASH)

• Family history of liver cancer; male >40 years

• Regular exposure to aflatoxin from poorly stored foods

Red-flag symptoms

Unintentional weight loss, right-upper-quadrant pain/pressure, jaundice, abdominal swelling/ascites, dark urine, generalized itching, persistent fatigue. Don’t wait.

Standard surveillance (for “at-risk” individuals)

• Abdominal ultrasound + AFP blood test: every 6 months

• Liver function, HBV/HCV tests, and fibrosis assessment as indicated

• If ultrasound is suspicious → triphasic CT/MRI for confirmation and staging

Why 6 months? Fast-growing HCCs can be missed with longer intervals.

Prevention that works

• Hepatitis B vaccination for non-immune individuals

• Curative treatment for hepatitis C when eligible

• Reduce/stop alcohol; manage weight, diabetes, and lipids

• Be cautious with herbal/OTC pain meds; use only with medical advice

• Food safety—avoid moldy nuts/grains and poorly stored dried foods

If a lesion is found

Your care team will tailor therapy to tumor stage and liver reserve: surgical resection, thermal ablation (RFA/MWA), trans-arterial therapies (e.g., TACE), and systemic targeted/immunotherapy; coordinated referral for advanced options when needed.

Why Thonburi Trang Hospital

• Dedicated GI & Liver Clinic led by gastroenterologists

• Structured surveillance with recall reminders

• On-site labs and imaging; rapid referral network for advanced treatment

FAQs

When should I start surveillance?
As soon as you know you’re at risk—especially with HBV/HCV or cirrhosis.

Do I need screening if I feel fine?
Yes. Early HCC is often asymptomatic; surveillance finds it when it’s treatable.

If my AFP is normal, am I safe?
Not necessarily. Ultrasound must accompany AFP to improve detection.

Is “occasional” drinking okay?
Risk rises with dose and frequency—especially if liver disease already exists.

Appointments & NAP

Thonburi Trang Hospital (THG) — GI & Liver Clinic
Tel 075-215-215 • Line/FB @THONBURITRANG • Open daily